BDBM25737 12-[(adamantan-1-ylcarbamoyl)amino]dodecanoic acid::CHEMBL215387::US10383835, Compound 700::Urea-based compound, 18

SMILES OC(=O)CCCCCCCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2

InChI Key InChIKey=XLGSEOAVLVTJDH-UHFFFAOYSA-N

Data  44 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25737   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM25737(12-[(adamantan-1-ylcarbamoyl)amino]dodecanoic acid...)
Affinity DataIC50:  107nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed